MESOcontroller - mesoView Co., Ltd.

Laser Scan Controller- LSC100

A Compact, All-in-One Control Platform Optimized for High-Speed Optical Microscopy"

LSC100 is a high-performance Laser Scan Controller designed for systems employing high-speed resonant scanners. It supports ultrafast acquisition up to 1500 fps (4 channels, 16 Y-lines), enabling high-speed functional imaging with precise temporal fidelity. With its One-Click Kilohertz FieldShift™ (kHz-FS™) technology, users can instantly shift from large-FOV mesoscopic imaging to localized kilohertz-rate scanning — ideal for calcium or voltage imaging, neural dynamics, and high-speed optogenetics. LSC100 further provides an ultrahigh digital resolution — up to 8192 × 8192 pixels per frame. Its Rapid Artifact-Compensated 2D Large-Field Mosaic-Stitching (rac2D-LMS™) delivers gigapixel scanning of centimeter-scale areas up to 20 mm × 20 mm (up to 57000 × 57000 px) in real time with automatic, GPU-accelerated stitching algorithms. Powered by the GPU-accelerated mesoXScan™ software suite, LSC100 delivers true real-time, artifact-free imaging from scanner to screen. LSC100 integrates scanner drivers, high-voltage controllers, raster-scanning electronics, stepper-motor and LED drivers, multi-sensor interfaces, and laser-safety control into a single compact enclosure.

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MESOcontroller

Adaptable design (Ex vivo experiment)

Unmatched Control & Capabilities

Experience the power of mesoController with its all-in-one design and precision-engineered features.

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Kilohertz Imaging Capability

Up-to 1500 fps laser-scanning (4 channels, 16 Y-lines) — Ideal for calcium imaging, voltage imaging, neural dynamics, and high-speed optogenetics.

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Ultrahigh Digital Resolution

Up-to 8192 × 8192 pixels per frame to reveal cellular and subcellular detail at pixel size <0.2 µm — ideal for stitching-free large-area imaging.

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One-Click Kilohertz FieldShift™

From a mesoscopic overview to high-speed cellular dynamics in a single click — instantly boost the frame rate to kilohertz speed and visualize rapid activity within the selected region — seamlessly overlaid on the full field.

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Rapid Artifact-Compensated 2D Large-Field Mosaic-Stitching (rac2D-LMS™)

Gigapixel scanning of centimeter-scale area up to 20 mm × 20 mm (up to 57000 × 57000 px) in real time with automatic, GPU-accelerated stitching algorithms — No post-processing needed.

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True Real-Time Imaging with mesoXScan™

From scanner to screen within milliseconds — GPU-accelerated mesoXScan™ software suite enables near real-time distortion correction and calibration to deliver live visualization.

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Jitter-Suppressed Triggering

Built-in phase-locked loop (PLL) for line-synchronized triggering — ensures artifact-free imaging.

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Integrated Laser Safety

Native control of laser-safety shutter — real-time sensor feedback ensures secure operation.

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Firmware Flexibility

Configurable firmware — supports external frame/trigger I/O, analog and I²C sensors/peripherals, stepper-motor and LED drivers, adapting seamlessly to your experimental needs.

Technical Specifications

Detailed specifications for our mesoController to help you choose the perfect configuration for your imaging system.

Model	MESOscope Pro
Operating channels	Up to 4 parallel channels
Resonant scanner	4 kHz or 8 kHz or 12 kHz *Supports scanners from: Cambridge Technology, Electro-Optical Products Corporation (EOPC)
Galvanometer scanner	Supports scanners from: Cambridge Technology, Thorlabs
Jitter-free line trigger	Supports phase-locked loop trigger system for jitter-suppressed line triggering
Ultrafast sampling	Yes Up to 500 M/s (2 channels) Up to 125 M/s (4 channels) or Up to 160 M/s (2 channels) Up to 80 M/s (4 channels)
High-speed imaging	Up to 800 fps
Max. image size	8192 × 8192 (4 kHz) *Subject to laser repetition rate
Bidirectional scan	Yes
PMT controller	Up to 4 PMTs, each channel providing up to –1200V
3D stage	Supports linear stages from Zaber Technologies
Laser safety	Supports automatic motorized shutter mechanism
External trigger	Supports external triggering for acquisition control (for synchronizing with experimental setup)
Software	Includes GPU-accelerated software mesoXScan for acquisition and data processing
Dimensions	323 mm × 282 mm × 48 mm (approx.)
Operating temperature	20–35 °C
Power input	125/250V AC, 50/60 Hz

Laser Scan Controller- LSC100